What do you know about Amantadine ?

Amantadine class is a medication primarily used to treat and prevent certain types of viral infections and to manage symptoms of Parkinson’s disease. Here are some key points about it:

1. Mechanism of Action:
   • It has antiviral properties, particularly against the influenza A virus, by inhibiting viral replication.
   • In Parkinson’s disease, it may enhance dopamine release and block dopamine reuptake, which can help alleviate motor symptoms.
2. Uses:
   • Influenza: Often prescribed for the prevention and treatment of influenza A.
   • Parkinson’s Disease: Used to treat symptoms such as tremors and stiffness.
   • Post-encephalitic Parkinsonism: Can be used in patients who have developed Parkinson-like symptoms after a viral infection.
3. Forms:
   • Amantadine class is available in various forms, including capsules, tablets, and syrup.
4. Side Effects:
   • Common side effects may include nausea, dizziness, insomnia, and dry mouth.
   • More serious side effects can include confusion, hallucinations, and worsening of existing mental health conditions, particularly in older adults.
5. Precautions:
   • Caution is advised for patients with a history of seizures, heart problems, or renal impairment, as dosage adjustments may be necessary.
6. Drug Interactions:
   • Amantadine class can interact with other medications, so it’s important for patients to discuss all their current medications with their healthcare provider.
7. COVID-19 Research:
   • Some studies have explored the potential use of it in treating COVID-19, though its efficacy for this purpose is still under investigation.