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What do you know about Phentermine?
Phentermine is a prescription medication primarily used as an appetite suppressant for short-term management of obesity. It belongs to a class of drugs known as sympathomimetic amines that are chemically related to amphetamines. Phentermine works by stimulating the central nervous system, which increases heart rate and blood pressure while decreasing appetite.
Here’s a more detailed overview:
How It Works:
Phentermine affects certain neurotransmitters in the brain—specifically norepinephrine, dopamine, and serotonin. This action helps reduce hunger and increases energy expenditure, making it easier for people to control their calorie intake.
Uses:
- Weight Loss: Phentermine is prescribed as part of a broader weight-loss plan that includes dietary changes, exercise, and behavioral modifications. It’s typically recommended for individuals with a body mass index (BMI) of 30 or higher or a BMI of 27 or higher with weight-related conditions like hypertension, diabetes, or dyslipidemia.
- Short-Term Use: The FDA has approved phentermine for short-term use, usually a few weeks, because its long-term safety has not been well studied.
Common Side Effects:
- Dry mouth
- Insomnia
- Increased heart rate
- Nervousness or anxiety
- Constipation
- Elevated blood pressure
Serious Side Effects (Rare):
- Heart palpitations
- Shortness of breath
- Chest pain
- Severe mood changes
Precautions and Contraindications:
Phentermine is not recommended for people with a history of cardiovascular diseases, including heart disease, high blood pressure, or stroke. It can also interact negatively with other medications, especially monoamine oxidase inhibitors (MAOIs) or certain antidepressants. It is not suitable for use during pregnancy or breastfeeding.
Potential for Abuse:
Because phentermine is chemically similar to amphetamines, it has the potential for abuse and dependence. For this reason, it is classified as a Schedule IV controlled substance in the U.S., meaning it has a lower abuse potential than Schedule II or III drugs but still needs to be carefully monitored.
Common Brand Names:
- Adipex-P
- Lomaira
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