What do you know about Meloxicam?

Meloxicam 15 mg is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce inflammation, pain, and fever. It is commonly prescribed for conditions like osteoarthritis and rheumatoid arthritis. Meloxicam works by inhibiting cyclooxygenase (COX) enzymes, specifically COX-2, which play a role in the production of prostaglandins—chemicals that trigger inflammation, pain, and fever in the body.

Key Points:

1. Uses:
   • Primarily used to treat osteoarthritis and rheumatoid arthritis.
   • Can also be prescribed for other inflammatory conditions.
2. Mechanism of Action:
   • Meloxicam 15 mg selectively inhibits COX-2 more than COX-1, which may lead to fewer gastrointestinal side effects compared to other NSAIDs that inhibit both enzymes more equally.
3. Common Side Effects:
   • Gastrointestinal issues: nausea, upset stomach, and diarrhea.
   • Dizziness and headaches.
   • May increase the risk of heart-related issues (like heart attack or stroke), especially with long-term use or at higher doses.
4. Serious Risks:
   • Cardiovascular risks: Long-term use of NSAIDs, including Meloxicam 15 mg, may increase the risk of heart attack or stroke.
   • Gastrointestinal risks: Though it’s thought to be safer for the stomach compared to some other NSAIDs, it can still cause ulcers, bleeding, or perforation in the stomach or intestines, especially in elderly individuals.
   • Kidney function: Like other NSAIDs, Meloxicam may reduce kidney function, particularly in individuals with pre-existing kidney problems.
5. Dosing:
   • It is typically taken once daily due to its long half-life, which allows for less frequent dosing compared to other NSAIDs.
6. Precautions:
   • Should not be taken during the third trimester of pregnancy due to potential harm to the fetus.
   • Avoid if there is a history of severe allergic reactions to other NSAIDs or aspirin.
   • People with a history of stomach ulcers, kidney disease, or cardiovascular conditions should use Meloxicam 15 mg with caution and under close medical supervision.
7. Forms:
   • Available in tablets, oral suspensions, and sometimes injections.