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What do you know about Aspirin ?
Aspirin structure also known as acetylsalicylic acid (ASA), is a widely used nonsteroidal anti-inflammatory drug (NSAID). It has a range of uses, primarily for:
1. Pain Relief:
Aspirin structure is effective in treating mild to moderate pain, such as headaches, toothaches, and muscle aches.
2. Anti-inflammatory:
It reduces inflammation by inhibiting an enzyme called cyclooxygenase (COX), which plays a key role in the production of prostaglandins, compounds involved in inflammation.
3. Antipyretic (fever reducer):
Aspirin structure helps lower fever by acting on the hypothalamus, the part of the brain that regulates body temperature.
4. Prevention of Clots:
In addition to its cardiovascular benefits, Aspirin structure can be used after certain surgeries (e.g., heart bypass surgery) to prevent blood clot formation.
Common Side Effects:
- Gastrointestinal Issues: Prolonged use can lead to stomach irritation, ulcers, and bleeding, as prostaglandins also protect the stomach lining.
- Bleeding Risks: Because it affects blood clotting, aspirin can increase the risk of bleeding, especially in people taking other blood thinners.
Special Considerations:
- Reye’s Syndrome: Aspirin structure should not be given to children or teenagers recovering from viral infections (like the flu or chickenpox) because it has been linked to Reye’s syndrome, a rare but serious condition that causes swelling in the liver and brain.
- Asthma Patients: Some people with asthma may have a sensitivity to aspirin, leading to bronchospasm or worsening of asthma symptoms.
Historical Background:
It was first synthesized by the German chemist Felix Hoffmann at Bayer in 1897, although its active ingredient (salicylic acid) had been used in herbal remedies for centuries, notably in willow bark.
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