Common Side Effects:

1. Skin Irritation: Redness, itching, or rash at the application site.
2. Burning Sensation: Some users may feel a mild burning sensation where the patch is applied.
3. Dermatitis: Localized skin inflammation or dermatitis can occur.

Less Common Side Effects:

1. Allergic Reactions: Symptoms may include rash, hives, swelling, or difficulty breathing. This requires immediate medical attention.
2. Nausea or Upset Stomach: Although systemic absorption is lower, some individuals may still experience gastrointestinal symptoms.
3. Headache: Some users may report headaches as a side effect.
4. Dizziness or Lightheadedness: Though less common, some may experience dizziness after application.

Rare but Serious Side Effects:

1. Severe Skin Reactions: Such as blisters or peeling skin, which may require medical intervention.
2. Heart Issues: Prolonged use of NSAIDs has been linked to increased risk of heart attacks or strokes, though this risk is lower with topical formulations.
3. Kidney Problems: Although rare, systemic absorption may lead to kidney-related issues.

Precautions:

• Not for Open Wounds: Do not apply the patch on open wounds or broken skin.
• Avoiding Exposure: It’s advisable to avoid exposing the patch to direct sunlight or heat, as this may increase the risk of skin irritation.
• Consult a Healthcare Provider: Before using the patch, individuals with a history of allergic reactions to NSAIDs or other medications should discuss this with their healthcare provider.