What do you know about Ambien CR?

Ambien CR vs Ambien is a prescription medication primarily used for treating insomnia, specifically difficulty falling asleep and staying asleep. It belongs to a class of drugs called sedative-hypnotics, and its generic name is zolpidem tartrate. Ambien CR differs from regular Ambien in that it has a two-layered structure:

• First layer: Dissolves quickly to help you fall asleep shortly after taking it.
• Second layer: Releases more slowly throughout the night to help you stay asleep longer.

Key Points about Ambien CR:

1. Mechanism of Action: It works by enhancing the effects of a neurotransmitter in the brain called GABA (gamma-aminobutyric acid), which has calming effects that help induce sleep.
2. Dosage and Administration:
   • It comes in extended-release tablets, typically in strengths of 6.25 mg or 12.5 mg.
   • It should be taken once a night immediately before bedtime, and you should have at least 7–8 hours of sleep before needing to be active again.
3. Potential Side Effects:
   • Common: Drowsiness, dizziness, headache, nausea, or dry mouth.
   • Serious but rare: Sleepwalking, sleep-driving, or engaging in other activities while not fully awake. These activities can be dangerous because individuals may have no memory of them.
4. Warnings:
   • Addiction and dependence: Zolpidem can be habit-forming, especially with long-term use. It’s usually prescribed for short-term treatment (2 to 4 weeks).
   • Cognitive or motor impairment: Ambien CR can cause next-day drowsiness or impair cognitive and motor functions, affecting activities like driving or operating machinery.
   • Alcohol: Drinking alcohol while on Ambien CR can increase its sedative effects, leading to dangerous side effects.
5. Precautions:
   • Should be used with caution in the elderly, as they may be more sensitive to its effects.
   • People with a history of depression, anxiety, or substance abuse should disclose this to their doctor, as Ambien CR can exacerbate these conditions.
   • It is not recommended for individuals with severe liver disease due to reduced metabolism of the drug.