What do you know about Aripiprazole ?

Aripiprazole 10 mg is an atypical antipsychotic medication primarily used to treat a variety of mental health conditions. It works by affecting certain neurotransmitters in the brain, particularly dopamine and serotonin, which play a role in mood, behavior, and cognition. Here’s a more detailed breakdown of its uses, mechanism, and side effects:

Mechanism of Action:

Aripiprazole 10 mg works as a dopamine partial agonist and serotonin receptor modulator. Unlike typical antipsychotics, which block dopamine receptors, aripiprazole acts in a more balanced way by partially stimulating dopamine receptors (especially D2) and also modulating serotonin receptors. This can help reduce the risk of some side effects like sedation and weight gain, which are more common with other antipsychotics.

Forms and Dosage:

• It is available in various forms: oral tablets, orally disintegrating tablets, liquid formulations, and an extended-release injectable form.

Side Effects:

• Common: Anxiety, insomnia, headache, nausea, vomiting, dizziness, weight gain, and restlessness (akathisia).
• Less Common: Blurred vision, constipation, increased appetite, tremors, and fatigue.
• Serious: Tardive dyskinesia (involuntary movements), neuroleptic malignant syndrome (a rare but life-threatening condition), and increased risk of suicidal thoughts in young people.

Warnings and Precautions:

1. Metabolic Changes: Like other atypical antipsychotics, aripiprazole can cause metabolic changes such as increased blood sugar, cholesterol, and weight gain in some individuals.
2. Elderly with Dementia-Related Psychosis: There is an increased risk of death for elderly patients with dementia-related psychosis when treated with antipsychotic drugs like aripiprazole.
3. Impulsivity: Some users have reported increased impulsive behaviors (such as gambling or overeating), particularly when taking higher doses.
4. Drug Interactions: Aripiprazole 10 mg can interact with other medications, including certain antidepressants, antifungals, and anticonvulsants.

Withdrawal:

Abrupt discontinuation of aripiprazole can lead to withdrawal symptoms, such as nausea, vomiting, insomnia, and return of psychotic symptoms.