What do you know about ketoprofen?

Ketoprofen tablet is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, inflammation, and fever. It’s part of the propionic acid class of NSAIDs, similar to ibuprofen and naproxen. Here are some key aspects of ketoprofen:

1. Mechanism of Action:

• Ketoprofen tablet works by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which play a critical role in the synthesis of prostaglandins. Prostaglandins are compounds involved in pain, inflammation, and fever. By reducing prostaglandin production, ketoprofen reduces inflammation, pain, and fever.

2. Uses:

• Anti-inflammatory: Used to manage conditions such as rheumatoid arthritis and osteoarthritis.

3. Forms and Administration:

• Oral Tablets/Capsules: The most common form for systemic use.
• Topical Gel: Applied directly to the skin to relieve localized pain and inflammation, often used for joint or muscle pain.

4. Side Effects:

Like other NSAIDs, Ketoprofen tablet can have several side effects, including:

• Gastrointestinal Issues: Common side effects include stomach upset, heartburn, nausea, and in more severe cases, gastric ulcers or bleeding.
• Cardiovascular Risk: Prolonged use of ketoprofen may increase the risk of heart attack or stroke, similar to other NSAIDs.
• Kidney Effects: It may impair kidney function, particularly in people with preexisting kidney issues.
• Allergic Reactions: Some people may experience rashes, difficulty breathing, or other allergic symptoms.

5. Contraindications:

• Individuals with peptic ulcer disease, severe heart failure, or renal impairment should avoid ketoprofen.

6. Interactions:

• Ketoprofen tablet  may interact with other medications, such as blood thinners (e.g., warfarin), ACE inhibitors, diuretics, and other NSAIDs, potentially increasing the risk of side effects.

It’s essential to use it under medical supervision, especially if there are preexisting health conditions.