What do you know about Sprix?
SPRIX nasal spray is a nasal spray form of ketorolac tromethamine, a non-steroidal anti-inflammatory drug (NSAID).
However, it comes with certain risks typical of NSAIDs, such as gastrointestinal issues, bleeding, and potential cardiovascular complications. As a result, its use is limited to five days to minimize these risks
Benefits:
The benefits of Sprix nasal spray (ketorolac tromethamine) include:
- Fast-Acting Relief: SPRIX nasal spray offers rapid pain relief, typically within 20 to 30 minutes, making it effective for managing acute moderate to moderately severe pain
- Non-Opioid Alternative: It provides an analgesic effect comparable to opioids but without the risk of opioid dependency, addiction, or abuse
- Convenience: As a nasal spray,it eliminates the need for injections, offering a more accessible and easy-to-administer form of ketorolac, especially for outpatient care
- Reduction in Opioid Use: In clinical studies, SPRIX nasal spray demonstrated a reduction in the need for opioid medications by 26-36% when used in combination with morphine, further minimizing opioid exposure
Side Effects:
It (ketorolac tromethamine) nasal spray can cause several side effects, ranging from mild to severe. Some of the most common side effects include:
- Gastrointestinal issues: Ketorolac, like other NSAIDs, can cause stomach upset, nausea, diarrhea, and in severe cases, peptic ulcers or gastrointestinal bleeding. These effects can be serious and potentially life-threatening
- Bleeding risks: It inhibits platelet function, which can lead to bleeding complications, especially in individuals with a history of bleeding disorders or those taking anticoagulant medications
- Cardiovascular risks: NSAIDs may increase the risk of serious cardiovascular events such as myocardial infarction (heart attack) and stroke, particularly with prolonged use.
- Renal (kidney) issues: Prolonged use of ketorolac can lead to kidney damage or failure, especially in individuals with pre-existing renal conditions
- Allergic reactions: In rare cases, individuals may experience allergic reactions such as rash, swelling, or difficulty breathing
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